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Congenital Trypanosoma cruzi Infection. Efficacy of Its Monitoring in an Urban Reference Health Center in a Non-Endemic Area of Argentina

机译：先天性克氏锥虫感染。在阿根廷非疫区的城市参考医疗中心进行监测的功效

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Congenital transmission (CT) has acquired relevance in Chagas disease (CHD). A cohort of pregnant CHD women (4,355) and their babies were studied in the period 1994–2004. Children were excluded when they had received blood transfusions, or were born or had been in endemic areas; CT rate was 6.1%. Babies were diagnosed between months 1 and 5 in 68.9% of the cases and between months 6 and 12 in 31.1%. In the latter group, parasitemia was detected in 94% and serology in 74.7%. Between months 6 and 9, parasitemia diagnosed 36.2% (P = 0.000) more cases than serology. If serology had been the diagnosis method, those children would have been considered CT free. Taking the overall outcomes, 38.1% of babies were CT free, and 55.8% did not complete the follow-up. Establishing CT as a public health priority and improving first-line health service, congenital CHD coverage could be more efficient in endemic countries.
机译：先天性传播（CT）已与查加斯病（CHD）相关。在1994年至2004年期间对一组冠心病孕妇（4,355名）及其婴儿进行了研究。接受输血，出生或曾在流行地区的儿童被排除在外； CT检查率为6.1％。 68.9％的病例在第1个月至第5个月之间被诊断为婴儿，而31.1％的病例在6个月至12个月之间被诊断为婴儿。在后一组中，检出寄生虫病的占94％，血清学检出的占74.7％。在6到9个月之间，寄生虫病比血清学诊断出的病例多36.2％（P = 0.000）。如果将血清学作为诊断方法，则这些儿童将被视为无CT。从总体结果来看，38.1％的婴儿没有CT检查，而55.8％的孩子没有完成随访。将CT确立为公共卫生的重点并改善一线医疗服务，在流行国家，先天性CHD的覆盖范围可能会更有效。

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